过氧化爆炸物易于制备、难于检测的特性使其备受恐怖分子青睐，这却给分析检

过氧化爆炸物易于制备、难于检测的特性使其备受恐怖分子青睐，这却给分析检测带来巨大挑战。本研究以苯偶酰为识别基团，二氟化硼二吡咯甲烷（BODIPY）为荧光团，通过设计、合成了新型荧光探针BD-3，并对其化学结构进行分析表征。基于光致诱导电子转移（PET）机理，该探针自身仅有较弱的荧光，响应H2O2之后其荧光强度实现比率型增强（I508/I499=11），发射较强的绿色荧光，具备裸眼可见。同时，BD-3对H2O2线性响应范围为1 × 10-6 ~ 1 × 10-4 M，相关系数R=0.996，检出限为0.88 μM。另外，BD-3具有很好的光稳定性和对H2O2的高选择性响应。总之，本研究发展的新型探针具有光稳定性好、选择性高和对H2O2的荧光增强响应等优点，可满足复杂环境条件下过氧化爆炸物的现场检测需求。

結果 (英文) 1:

Peroxide explosives are easy to prepare, is difficult to detect characteristics make it highly favored by terrorists, which pose great challenges for analysis. Benzil to identify groups of this study, boron difluoride methylene pyrrole (BODIPY) as a group, through the design and synthesis of novel fluorescent probes BD-3 and analysis of its chemical structure. Induction based photoinduced electron transfer (PET) mechanism of the probe itself has only weak fluorescent response to H2O2 the implementation ratio-enhanced fluorescence intensity (I508/I499=11), launched a strong green fluorescence and visible to the naked eye. Meanwhile, BD-3 response to H2O2 linear range 1x10-6 ~ 1x10-4 m, correlation coefficients R=0.996, detection limit to 0.88 m. In addition, BD-3 has excellent light stability and high selectivity response to H2O2. In General, the research and development of new type probe has good stability, high selectivity and the advantages of fluorescence-enhanced response to H2O2, can meet complex peroxide explosives under the environmental conditions of the site inspection needs.

結果 (英文) 2:

Peroxide explosives ease of preparation, properties make it difficult to detect the highly favored by terrorists, which gave analysis detected a huge challenge. In this study, benzil as recognition group, boron difluoride dipyrromethane (BODIPY) fluorophore, through the design, synthesis of novel fluorescent probes BD-3, and to characterize its chemical structure. Visible on the photo-induced electron transfer (PET) mechanism, the probe itself is only a weak fluorescence, the fluorescence intensity after the response to H2O2 ratiometric type enhancement (I508 / I499 = 11), emitted strong green fluorescence, with the naked eye . Meanwhile, BD-3 on H2O2 linear response range of 1 × 10-6 ~ 1 × 10-4 M, the correlation coefficient R = 0.996, a detection limit of 0.88 μM. In addition, BD-3 has good light stability and high selectivity of the response to H2O2. In short, the new probe of the present research and development with good light stability, high selectivity and fluorescence enhancement of H2O2 response, etc., to meet the complex environment peroxide explosives site testing requirements.

結果 (英文) 3:

It has been favored by the terrorists to make it easy to be prepared and difficult to detect, which brings great challenge to the analysis and detection. In this study, a novel fluorescent probe BD-3 was designed and synthesized, and its chemical structure was characterized by the design and synthesis of a novel fluorescent probe BODIPY, which was identified as the group of two boron fluoride (two). Photo induced electron transfer (PET) mechanism, based on the fluorescence of the probe itself is only weak, in response to the H2O2 after the fluorescence intensity ratio (I508/I499=11) to achieve enhanced green fluorescent emission, strong, have visible with the naked eye. At the same time, the linear response range of BD-3 to H2O2 is 1 * 10-6 ~ 1 * M 10-4, the correlation coefficient is R=0.996, the detection limit is 0.88 mu M. In addition, BD-3 has very good light stability and high selectivity to H2O2. In conclusion, the development of this new type of probe has the advantages of good light stability, high selectivity and fluorescence enhancement response to H2O2, which can meet the needs of the field detection of peroxide explosive in complex environmental conditions.